Most nootropics are not approved by the US Food and Drug Administration (FDA) for the treatment of any medical condition. However, some prescription drugs used for conditions such as ADHD and narcolepsy, such as Modafinil and Ritalin, have been approved by the FDA and are considered nootropics by some definitions. Additionally, some natural compounds that are classified as dietary supplements, such as caffeine, are not regulated by the FDA for their cognitive-enhancing effects. It is important to note that just because a nootropic is not FDA-approved does not necessarily mean it is unsafe or ineffective. However, it is always recommended to speak with a healthcare professional before using any nootropic, especially if you have a medical condition or are taking medication.