The ADHD medication classified as an alpha-agonist is guanfacine (brand name: Intuniv). It is a non-stimulant medication that works by targeting alpha-2A adrenergic receptors in the brain. By doing so, guanfacine can improve attention and impulse control in people with ADHD. Guanfacine is often prescribed to children and adolescents with ADHD who cannot tolerate or do not respond well to stimulant medications. It may also be used in combination with a stimulant medication to enhance the effects of both drugs. As with any medication, it is important to work closely with a healthcare provider to determine if guanfacine is an appropriate treatment option for your individual needs.