In general, BCAA supplements are considered safe for healthy adults when taken in the recommended doses. However, there are some individuals who should avoid or limit their intake of BCAAs, including:
- People with ALS (amyotrophic lateral sclerosis) or branched-chain ketoaciduria, as they have difficulty metabolizing BCAAs.
- Individuals with a history of liver disease or impaired liver function, as excessive intake of BCAAs can worsen liver function.
- People with maple syrup urine disease, a rare genetic disorder that affects how the body processes certain amino acids, including BCAAs.
As with any supplement, it's important to talk to your healthcare provider before taking BCAA supplements, especially if you have a pre-existing medical condition or are taking any medications.